Would you volunteer for a human challenge trial to speed up COVID-19 vaccine development? | The Tylt

Would you volunteer for a human challenge trial to speed up COVID-19 vaccine development?

One of the biggest challenges to vaccine development is determining whether or not the vaccines themselves are safe and effective. The standard process is typically slow and takes a long time to determine results. Challenge trials speed up this process by taking healthy adult volunteers and deliberately exposing them to the virus in a controlled setting to see if the vaccine will work. Critics of the idea argue that COVID-19 is too risky—there is no good treatment for it if people ultimately become severely ill. However, proponents say the benefits outweigh the risks—healthy young adults are not likely to become severely ill. The time saved on vaccine development could save thousands of lives and allow humanity to get back to a new normal.

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Would you volunteer for a human challenge trial to speed up COVID-19 vaccine development?
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Would you volunteer for a human challenge trial to speed up COVID-19 vaccine development?
#UseChallengeTrials
#DontPutLivesAtRisk
#UseChallengeTrials

Volunteers and proponents of a challenge trial say that any work taken to accelerate the development of a COVID-19 vaccine would be worth it. Normally, vaccine trials require a lot of time for real world situations to unfold. People are first given the vaccine, then they are tracked over a period of time to see how they respond when they become naturally exposed to the virus. 

A challenge trial would allow researchers more control over that process—in a laboratory setting, researchers could uniformly expose healthy volunteers who have responded well to the vaccine to the virus and then precisely see what protective effects the vaccine would provide. This would allow researchers to quickly determine whether or not the vaccine works well enough—saving lives in the process by getting a vaccine to market sooner. 

#UseChallengeTrials
#UseChallengeTrials
#UseChallengeTrials
#DontPutLivesAtRisk

The biggest argument against human challenge trials is that it is unclear if it is ethically justified. Without an effective treatment for the disease, a human challenge trial with COVID-19 would very well risk the deaths of some of the participants. Limiting the pool of participants to healthy young adults without pre-conditions would go a long way in limiting those risks based on our knowledge of the virus, but, ultimately, that is no guarantee. There is still a lot we don't know about this virus. 

Another issue is that a challenge trial may not necessarily speed up the process where it's most needed—we've already seen that the disease has the largest impact on older people who are immunocompromised or have pre-existing conditions. A challenge trial consisting of only healthy young adults would not provide the critical information needed, which would limit the benefits of a challenge trial. 

#DontPutLivesAtRisk
#DontPutLivesAtRisk
#DontPutLivesAtRisk
FINAL RESULTS
Politics
Would you volunteer for a human challenge trial to speed up COVID-19 vaccine development?
A festive crown for the winner
#UseChallengeTrials
#DontPutLivesAtRisk